Category: Health and Medicine - Page 4
When Can Biosimilars Be Automatically Substituted? Understanding Interchangeability in the U.S.
Interchangeable biosimilars can be automatically swapped for brand-name biologics at the pharmacy level in the U.S., but only under strict FDA rules and varying state laws. Learn how they work, who can substitute them, and what patients need to know.
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Generic Prescribing Guidelines: What Doctors Need to Know in 2025
Discover the latest NHS and global guidelines on generic prescribing in 2025. Learn when to use generic drugs, which exceptions to watch for, how to handle patient concerns, and how to implement best practices in your practice.
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Foreign Manufacturing of Generics: FDA Oversight and Standards in 2025
Foreign-made generic drugs supply most of the U.S. market, but FDA oversight has been inconsistent. New unannounced inspections and stricter standards aim to close the gap-protecting patients from unsafe or ineffective medicines.
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How Pharmacists Verify Generic Equivalence: Practice Standards
Pharmacists use the FDA's Orange Book to verify that generic drugs are therapeutically equivalent to brand-name versions, ensuring safe and legal substitutions. This process relies on strict bioequivalence standards and state laws to protect patient safety.
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Rifampin Induction: How It Lowers Anticoagulant and Antiviral Levels
Rifampin can drastically lower levels of anticoagulants and antivirals by inducing liver enzymes, leading to dangerous drops in drug effectiveness. This interaction can cause blood clots, strokes, or treatment failure. Learn how to manage it safely.
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Warfarin and Generic Switching: What You Need to Know About INR Monitoring and Safety
Switching from brand-name warfarin to a generic version can be safe-but only with careful INR monitoring. Learn why even small changes in formulation matter, how to protect yourself from bleeding or clots, and what steps to take after a switch.
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Upper Airway Stimulation: An Implant Alternative for Sleep Apnea When CPAP Fails
Upper airway stimulation is an FDA-approved implant for sleep apnea that works when CPAP fails. It stimulates the tongue nerve to keep the airway open during sleep - no mask, no hose, no daily hassle.
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FDA’s Abbreviated New Drug Application Process Explained: How Generic Drugs Get Approved
The FDA's ANDA process lets generic drugmakers prove their products work just like brand-name drugs - without redoing costly clinical trials. This system saves billions and makes medicine affordable for millions.
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Rheumatoid Arthritis: Understanding Autoimmune Joint Damage and Modern Biologic Treatments
Rheumatoid arthritis is a chronic autoimmune disease that attacks joints, causing pain, swelling, and long-term damage. Biologic therapies target specific immune signals to slow progression, offering hope-but come with risks and high costs. Early treatment is critical.
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Cumulative Anticholinergic Burden: How Antihistamines Combine with Other Medications to Risk Cognitive Decline
Cumulative anticholinergic burden from antihistamines and other medications increases dementia and fall risks in older adults. Learn how to spot hidden drug interactions and switch to safer alternatives.
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